Expert answer:Functional Groups and Drug Structures

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Solved by verified expert:Can someone with a Chemistry background help me answer these questions in this assignment? It’s related to Chemistry Drug Structures and Functional Groups, and has to be a max of 500 words. Thank you!
chemassignment.docx

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Task
The above compounds are important drugs. In this directed study please discuss
their physical and pharmaceutical properties.
Thereby, focus on the following:
– Name the functional groups
– Predict non-covalent interactions with targets / biological receptors (general
considerations); three for each drug
– Arrange these interactions from weaker to stronger
– What is the pKa and what does it tell us on the molecular level?
– Please predict the ionization of each molecule at pH 3 and pH 12. Name the
drugs and take their functional groups as the reason for their interactions with
receptors and their acid/base behaviour.
…
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