1. Ms. OV is a 75 year-old patient is currently receiving warfarin… 1. Ms. OV is a 75 year-old patient is currently receiving warfarin to prevent deep vein thrombosis. She comes to the clinic with an INR 12, despite taking the same dose of the drug. There is no evidence of bleeding. She was previously well controlled on warfarin.What is the best intervention for Ms. OV?A. Because Ms. OV’s INR is 12, warfarin therapy should be discontinued even though there are no signs of bleeding. She should also be given phytomenadione until the INR is reduced. Restart warfarin therapy when the INR <5. B. Because Ms. OV's INR is 12, warfarin therapy should be discontinued even though there are no signs of bleeding. It is also recommended to replace the warfarin with aspirin to prevent deep vein thrombosis C. Because Ms. OV's INR is 12 and there are no signs of bleeding, it is recommended to reduce the dose of warfarin. She should also be given phytomenadione until the INR is reduced. D. Because Ms. OV's INR is 12, warfarin therapy should be discontinued even though there are no signs of bleeding. She should also be given phytomenadione until the INR is reduced. Replace the warfarin with aspirin to prevent deep vein thrombosis. 2. Which of the following lipid-lowering agents should be avoided to a patient that is on warfarin therapy?A. NiacinB. AtorvastatinC. FenofibrateD. Cholestyramine 3. Mrs. BC is an 87-year-old woman diagnosed with AD 2 months ago. Her MMSE score at the time of diagnosis was 21. At that time, donepezil was started at a dose of 5 mg nightly at bedtime. Would it be considered appropriate to add memantine to her drug regimen this time?A. No, Mrs. BC has mild ADB. Yes, Mrs. BC is unlikely to respond to donepezilC. No, Memantine should never be added to cholinesterase inhibitor therapyD. Yes, Mrs. BC has moderate AD Biology Science Pharmacology
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