1.Consider the role of sodium dodecylsulfate, CH3(CH2)11OSO

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1.Consider the role of sodium dodecylsulfate, CH3(CH2)11OSO3- Na+,… 1.Consider the role of sodium dodecylsulfate, CH3(CH2)11OSO3- Na+, in SDS-PAGE. Suppose a biochemist were to explore the use of alternative detergents in PAGE experiments to obtain better molecular weight estimates of proteins. As alternatives to SDS, she decided to try the following:a. Dodecanol, which is CH3(CH2)11OH. Considering the molecular mechanism of SDS action in molecular weight determination, discuss how dodecanol would behave as a substitute for SDS. Would it be expected to lead to reliable molecular weight estimates? Explain.2. Docecylamine hydrochloride, which is CH3(CH2)11NH3+ Cl-. Compare and contrast this compound with SDS in how it would affect the proteins and the electrophoretic process. Should you expect it to give reliable molecular weight estimates? Explain. Chemistry Science Organic chemistry CHEG 991

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